| Identification | Back Directory | [Name]
Curzerene | [CAS]
17910-09-7 | [Synonyms]
Curzerene
Neocurzerene
Isogermafuren
Isogermafurene
Isofuranogermacrene
Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel- | [Molecular Formula]
C15H20O | [MDL Number]
MFCD23379925 | [MOL File]
17910-09-7.mol | [Molecular Weight]
216.32 |
| Chemical Properties | Back Directory | [Boiling point ]
282.8±40.0℃ (760 Torr) | [density ]
0.982±0.06 g/cm3 (20 ºC 760 Torr) | [Fp ]
117.5±14.2℃ | [solubility ]
Soluble in chloroform | [form ]
liquid | [color ]
Yellow oily | [InChI]
InChI=1/C15H20O/c1-6-15(5)8-14-12(11(4)9-16-14)7-13(15)10(2)3/h6,9,13H,1-2,7-8H2,3-5H3/t13-,15+/s3 | [InChIKey]
HICAMHOOTMOHPA-MJZDCSSWNA-N | [SMILES]
O1C2C[C@@](C=C)(C)[C@@H](C(C)=C)CC=2C(C)=C1 |&1:3,7,r| | [LogP]
3.982 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Curcuma zedoaria. | [Uses]
Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis[1]. | [References]
[1] Wang Y, et al. Cytotoxic and Antitumor Effects of Curzerene from Curcuma longa. Planta Med. 2017 Jan;83(1-02):23-29. DOI:10.1055/s-0042-107083 |
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