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180409-60-3

180409-60-3 Structure

180409-60-3 Structure
IdentificationBack Directory
[Name]

CYFLUFENAMID
[CAS]

180409-60-3
[Synonyms]

nf-149
CYFLUFENAMID
CyflufenaMide
CYFLUFENAMID STANDARD
100 μg/mL in Acetonitrile
cyflufenamid (bsi, pa iso)
Cyflufenamid@1000 μg/mL in Acetone
Cyflufenamid Solution in Acetonitrile, 1000μg/mL
N-{(Z)-[(Cyclopropylmethoxy)Amino][2,3-Difluoro-6-(Trifluoromethyl)Phenyl]Methylene}-2-Phenylacetamide
Benzeneacetamide, N-[[(cyclopropylmethoxy)amino][2,3-difluoro-6-(trifluoromethyl)phenyl]methylene]-, [N(Z)]-
[EINECS(EC#)]

202-303-5
[Molecular Formula]

C20H17F5N2O2
[MDL Number]

MFCD06656579
[MOL File]

180409-60-3.mol
[Molecular Weight]

412.35
Chemical PropertiesBack Directory
[Melting point ]

62.0℃
[density ]

1.36±0.1 g/cm3(Predicted)
[storage temp. ]

0-6°C
[form ]

neat
[pka]

9.34±0.46(Predicted)
[Major Application]

agriculture
environmental
[InChI]

1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)
[InChIKey]

ACMXQHFNODYQAT-UHFFFAOYSA-N
[SMILES]

Fc1ccc(c(c1F)C(\NC(=O)Cc2ccccc2)=N\OCC3CC3)C(F)(F)F
[LogP]

4.054 (est)
[EPA Substance Registry System]

Cyflufenamid (180409-60-3)
Safety DataBack Directory
[Symbol(GHS) ]

Environment (GHS09)
GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P391-P501
[Hazard Codes ]

Xn,N
[Risk Statements ]

20-50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Aquatic Chronic 1
Hazard InformationBack Directory
[Description]

Cyflufenamid is a preventative and curative fungicide. It has a low aqueous solubility and s non-volatile. It may be persistent in some soil and water systems depending on local conditions. The risk of leaching to groundwater is low. It is moderately toxic to aquatic organisms, but less so to birds and honeybees. It has a low oral mammalian toxicity and is an irritant.
[Uses]

Cyflufenamid-d5 is the isotope labelled analog of Cyflufenamid, which is a novel fungicide.
[Definition]

ChEBI: A member of the class of (trifluoromethyl)benzenes that is 2,3-difluoro-6-(trifluoromethyl)benzenecarboxamidine in which the hydrogen attached to the imino nitrogen is replaced by a cyclopropylmethoxy group while one of the hydrogens attached to the other itrogen is replaced by a phenylacetyl group. It is used as a fungicide for the control of powdery mildew in cereal crops as well as in apple and pear orchards.
[Production Methods]

Cyflufenamid is commercially produced through a multi-step organic synthesis involving fluorinated aromatic compounds. The process typically begins with the preparation of a substituted aniline derivative, which undergoes acylation and subsequent reactions to introduce the key functional groups, including the trifluoromethyl and cyano moieties that contribute to its biological activity. These steps are carried out under controlled conditions using specialised reagents and catalysts to ensure high yield and purity.
[Mechanism of action]

Preventative and curative activity, acts by inhibiting fungal development and disruption of haustorium formation and function.
[Pesticide Type]

Fungicide
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