| Identification | Back Directory | [Name]
Mal-PEG2-PFP | [CAS]
1807512-47-5 | [Synonyms]
Mal-PEG2-PFP
Mal-PEG2-PFP ester
perfluorophenyl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate
Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester | [Molecular Formula]
C17H14F5NO6 | [MDL Number]
MFCD26127799 | [MOL File]
1807512-47-5.mol | [Molecular Weight]
423.29 |
| Chemical Properties | Back Directory | [Boiling point ]
493.1±45.0 °C(Predicted) | [density ]
1.482±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [pka]
-2.34±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Mal-PEG2-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. | [Uses]
Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs; Alkyl/ether |
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| Company Name: |
Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
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http://www.nextpeptide.com/ |
| Company Name: |
Bide Pharmatech Ltd.
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400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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