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IdentificationBack Directory
[MDL Number]

MFCD26127800
Chemical PropertiesBack Directory
[Boiling point ]

452.8±45.0 °C(Predicted)
[density ]

1.541±0.06 g/cm3(Predicted)
[solubility ]

Soluble in DCM
[pka]

-2.34±0.20(Predicted)
Hazard InformationBack Directory
[Description]

Mal-PEG1-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
[Uses]

Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
[IC 50]

Alkyl/ether
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