| Identification | Back Directory | [Name]
CelosinI | [CAS]
1807732-38-2 | [Synonyms]
CelosinI
CelosinI USP/EP/BP
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranuronosyloxy)-2-hydroxy-, 28-(O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-6-deoxy-β-D-galactopyranosyl) ester, (2β,3β,4α)- | [Molecular Formula]
C53H82O24 | [MDL Number]
MFCD32197430 | [MOL File]
1807732-38-2.mol | [Molecular Weight]
1103.22 |
| Hazard Information | Back Directory | [Uses]
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice[1][2]. | [References]
[1] Wu QB, et al. Novel triterpenoid saponins from the seeds of Celosia argentea L. Nat Prod Res. 2013 Aug;27(15):1353-60. DOI:10.1080/14786419.2012.740034
[2] Pang X, et al. New oleanane-type triterpenoid saponins isolated from the seeds of Celosia argentea. J Asian Nat Prod Res. 2014;16(3):240-7. DOI:10.1080/10286020.2013.879120 |
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