| Identification | More | [Name]
4-Pyridineboronic acid pinacol ester | [CAS]
181219-01-2 | [Synonyms]
2-(4-PYRIDYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)PYRIDINE
4-PYRIDINEBORONIC ACID, PINACOL ESTER
4-PYRIDYLBORONIC ACID PINACOL ESTER
AKOS BRN-0440
PYRIDIN-4-YLBORONIC ACID, PINACOL ESTER
PYRIDINE-4-BORONIC ACID PINACOL CYCLIC ESTER
PYRIDINE-4-BORONIC ACID PINACOL ESTER
PYRIDINE-4-BORONIC PINACOLATE
4-Pyridineboronic acid, pinacol cyclic ester
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 4-Pyridylboronic acid pinacol ester | [EINECS(EC#)]
628-005-9 | [Molecular Formula]
C11H18BNO3 | [MDL Number]
MFCD01319051 | [Molecular Weight]
223.08 | [MOL File]
181219-01-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
149-153 °C (lit.) | [Boiling point ]
300.9±15.0 °C(Predicted) | [density ]
1.03±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator (+4°C) | [form ]
Powder | [pka]
4.32±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Insoluble | [BRN ]
7919059 | [InChI]
1S/C11H16BNO2/c1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9/h5-8H,1-4H3 | [InChIKey]
NLTIETZTDSJANS-UHFFFAOYSA-N | [SMILES]
CC1(C)OB(OC1(C)C)c2ccncc2 | [CAS DataBase Reference]
181219-01-2(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Preparation]
0.41 g of pyridineboronic acid and 0.39 g of pinacol were placed in a 50 mL round-bottom flask, and an appropriate amount of toluene was added as a solvent. The mixture was refluxed. Throughout the process, the evaporated water was continuously released from the system. After 4 hours, the reaction was stopped, and thin-layer chromatography (TLC) was used to check whether the reaction was complete. The round-bottom flask was cooled to room temperature and filtered to obtain 0.67 g of 4-Pyridineboronic acid pinacol ester as a white solid. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi,C,F | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
R11:Highly Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
No | [HazardClass ]
IRRITANT | [HS Code ]
29349990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Uses]
4-Pyridineboronic Acid Pinacol ester is used in dermatological preparations containing antioxidants and boron compounds for preventing damages to skin caused by peroxides. | [Uses]
It is employed in the synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors. |
| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 97%(181219-01-2) | [Alfa Aesar]
Pyridine-4-boronic acid pinacol ester, 98%(181219-01-2) | [Sigma Aldrich]
181219-01-2(sigmaaldrich) | [TCI AMERICA]
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine,>98.0%(GC)(T)(181219-01-2) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
skychemical Co.Ltd
|
| Telephone: |
021-20958197 20965099 |
| Website: |
www.skychemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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