| Identification | More | [Name]
ISONICOTINOYL CHLORIDE HYDROCHLORIDE | [CAS]
39178-35-3 | [Synonyms]
4-PYRIDINOYL CHLORIDE HYDROCHLORIDE
ISONICOTINOYL CHLORIDE HYDROCHLORIDE
ISONICOTINYL CHLORIDE HYDROCHLORIDE
PYRIDINE-4-CARBONYL CHLORIDE HYDROCHLORIDE
TIMTEC-BB SBB003768
pyridine-4-carbonyl chloride
ISONICOTINOYL CHLORIDE HYDROCHLORIDE, 95 %
Pyridine-4-carbonylchlorideHCl
IsonicotinoylchlorideHCl
4-Pyridinecarbonyl chloride hydrochloride
Isonicotinic acid chloride·hydrochloride | [EINECS(EC#)]
254-331-2 | [Molecular Formula]
C6H5Cl2NO | [MDL Number]
MFCD00012830 | [Molecular Weight]
178.02 | [MOL File]
39178-35-3.mol |
| Chemical Properties | Back Directory | [Appearance]
almost white to beige crystalline powder | [Melting point ]
159-161 °C(lit.)
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
methanol: soluble50mg/mL, clear to hazy, colorless to light yellow | [form ]
Crystalline Powder | [color ]
Almost white to beige | [Water Solubility ]
almost transparency | [Sensitive ]
Moisture Sensitive | [BRN ]
3626052 | [InChI]
InChI=1S/C6H4ClNO.ClH/c7-6(9)5-1-3-8-4-2-5;/h1-4H;1H | [InChIKey]
BNTRVUUJBGBGLZ-UHFFFAOYSA-N | [SMILES]
C1(C(Cl)=O)=CC=NC=C1.Cl | [CAS DataBase Reference]
39178-35-3(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive |
| Questions And Answer | Back Directory | [Uses]
Isonicotinyl Chloride Hydrochloride, is a heterocyclic building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the preparation of Tetrahydropyrroloquinolinone type dual inhibitors of Aromatase/Aldosterone Synthase, as a novel stagey for breast cancer patients with the risk of cardiovascular diseases. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Corrosive | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29333990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Ethanol-->Diethyl ether-->Sulfuric acid-->Dichloromethane-->Thionyl chloride-->Toluene-->Sodium chloride-->Isonicotinic acid-->Isonicotinic acid chloride | [Preparation Products]
propane-1,3-diyl diisonicotinate-->Pyridine-4-carboxylic acid pentafluorophenyl ester-->N-[2-(pyridine-4-carbonylamino)ethyl]pyridine-4-carboxamide-->4-Pyridinecarboxylic acid, 4,4'-(1,4-phenylene) ester-->but-2-yne-1,4-diyl diisonicotinate-->N-(4-Acetylphenyl)isonicotinamide-->tert-Butyl 4-(isonicotinamido)piperidine-1-carboxylate-->N-[(R)-9-Methyl-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-HI]indol-3-yl]isonicotinamide-->Methyl 2-(pyridin-4-yl)-1,3-benzoxazole-7-carboxylate |
|
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