| Identification | Back Directory | [Name]
CPPG | [CAS]
183364-82-1 | [Synonyms]
CPPG
rac-CPPG
(RS)-CPPG
(RS)-α-Cyclopropyl-4-phosphonophenylglycine
(RS)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE
(+/-)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE
Benzeneacetic acid, α-amino-α-cyclopropyl-4-phosphono- | [Molecular Formula]
C11H14NO5P | [MDL Number]
MFCD00673967 | [MOL File]
183364-82-1.mol | [Molecular Weight]
271.21 |
| Hazard Information | Back Directory | [Uses]
(RS)-CPPG is the most potent group II/III mGluR antagonist. | [Definition]
ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid. | [Biological Activity]
Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ . | [storage]
Room temperature |
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