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186501-28-0

186501-28-0 Structure

186501-28-0 Structure
IdentificationBack Directory
[Name]

Cal Green1 AM
[CAS]

186501-28-0
[Synonyms]

Cal Green1 AM
[Molecular Formula]

C59H53Cl2N3O26
[MOL File]

186501-28-0.mol
[Molecular Weight]

1290.96
Chemical PropertiesBack Directory
[Boiling point ]

1145.3±65.0 °C(Predicted)
[density ]

1.54±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
[pka]

12.13±0.70(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

Cal Green? 1 AM is a cell-permeant acetyloxy-methyl ester compound that is converted to the fluorescent calcium indicator Cal Green? 1 by intracellular esterases. This derivative is characterized by high quantum yield and low phototoxicity.1 Its peak excitation and emission wavelengths (506 and 531 nm, respectively) are comparable to standard fluorescein dyes, making Cal Green? 1 AM appropriate for fluorescent microscopy and flow cytometry. Cal Green? 1 is ~5-fold brighter than fluo-3 at saturating calcium levels.1
[Uses]

Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases[1].
[References]

1. Paredes, R.M., Etzler, J.C., Watts, L.T., et al. Chemical calcium indicators Methods 46(3),143-151(2008).
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