| Identification | More | [Name]
5-Bromo-2,3-difluorophenol | [CAS]
186590-26-1 | [Synonyms]
11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 21-ACETATE 17-ALPHA-HYDROXYCORTICOSTERONE ACETATE 17-HYDROXYCORTICOSTERONE 21-ACETATE 17-HYDROXYCORTICOSTERONE ACETATE 21-ACETOXY-4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-ACETOXY-4-PREGNENE-11BETA,17ALPHA-DIOL-3,20-DIONE 2,3-Difluoro-5-bromophenol 4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-ACETATE 4-PREGNEN-11BETA,17ALPHA,21-TETROL-3,20-DIONE 21-ACETATE 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-ACETATE 5-BROMO-2,3-DIFLUOROPHENOL ACETIC ACID 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-DIHYDROXY-10,13-DIMETHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER CORTISOL 21-ACETATE CORTISOL ACETATE DELTA4-PREGNEN-11BETA,17ALPHA-21-TRIOL-3,20-DIONE-ACETATE HYDROCORTISONE 21-ACETATE HYDROCORTISONE ACETATE HYDROCORTISONI ACETAS HYDROCORTONE ACETATE LANACORT | [EINECS(EC#)]
200-004-4 | [Molecular Formula]
C6H3BrF2O | [MDL Number]
MFCD00037714 | [Molecular Weight]
208.99 | [MOL File]
186590-26-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
223 °C (dec.)(lit.) | [Boiling point ]
65-66°C/0.1mm | [density ]
1.858±0.06 g/cm3(Predicted) | [refractive index ]
1.538 | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
clear liquid | [pka]
6.75±0.15(Predicted) | [color ]
White to Yellow to Green | [BRN ]
8831044 | [CAS DataBase Reference]
186590-26-1(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
5-Bromo-2,3-difluorophenol is an important intermediate in the synthesis of a large number of compounds with physiological or pharmacological activity. This compound can also be used to synthesize agrochemicals and liquid crystal compounds, and its applications are becoming increasingly widespread. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R63:Possible risk of harm to the unborn child. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3
| [RTECS ]
GM8960000
| [Hazard Note ]
Toxic | [HazardClass ]
IRRITANT | [HS Code ]
2908190090 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless transparent liquid | [Synthesis]
(1) To a 1000 mL four-necked reaction flask equipped with a magnet and a reflux condenser tube was added 84.4 g of 3,4,5- trifluorobromobenzene (0.4 mol), 500 mL of methanol and 67.2 g of
KOH (1.2 mol), the temperature was raised to 60 °C after the addit |
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