| Identification | Back Directory | [Name]
2B-(SP) | [CAS]
186901-17-7 | [Synonyms]
2B-(SP)
M.W. 1835.88 C71H123N26O29P
L-Leucine, L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-alanylglycyl-O-phosphono-L-seryl-L-prolyl-L-glutaminyl- (9CI) | [Molecular Formula]
C71H123N26O29P | [MDL Number]
MFCD06798312 | [MOL File]
186901-17-7.mol | [Molecular Weight]
1835.87 |
| Hazard Information | Back Directory | [Uses]
2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3[1]. | [IC 50]
GSK-3α; GSK-3β | [References]
[1] G I Welsh, et al. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts.Anal Biochem.?1997 Jan 1;244(1):16-21. DOI:10.1006/abio.1996.9838 |
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