Identification | More | [Name]
L(+)-Lactic acid | [CAS]
79-33-4 | [Synonyms]
2-HYDROXYPROPIONIC ACID L-(+)-2-HYDROXYPROPANOIC ACID L-2-HYDROXYPROPIONIC ACID LACTIC ACID L(+)-LACTIC ACID L-LACTIC ACID L-(+)-MILK ACID PURAC(R) 50 PURAC(R) HQ 88 PURAC(R) HS 88 PURAC(R) PF 88 PURAC(R) SP 80 PURAC(R) SP 88 (S)-(+)-2-HYDROXYPROPANOIC ACID (S)-2-HYDROXYPROPIONIC ACID SARCOLACTIC ACID (S)-(+)-LACTIC ACID (+)-Milchsαure (S)-Milchsαure 2-hydroxy-,(S)-Propanoicacid | [EINECS(EC#)]
201-196-2 | [Molecular Formula]
C3H6O3 | [MDL Number]
MFCD00064266 | [Molecular Weight]
90.08 | [MOL File]
79-33-4.mol |
Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
52-54°C | [alpha ]
-13.5 º (c=2.5, 1.5N NaOH) | [Boiling point ]
125 °C
| [density ]
1.206 g/mL at 25 °C
| [vapor pressure ]
0.038Pa at 25℃ | [FEMA ]
2611 | LACTIC ACID | [refractive index ]
n20/D 1.427
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
H2O: 10 mg/mL, clear, colorless
| [form ]
Powder/Solid | [pka]
pK at 25°, 3.79 | [color ]
White | [Odor]
odorless acidic | [Odor Type]
odorless | [optical activity]
[α]20/D 13.5°, c = 2.5 in 1.5 M NaOH | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Usage]
Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, | [JECFA Number]
930 | [Merck ]
14,5337 | [BRN ]
1720251 | [InChIKey]
JVTAAEKCZFNVCJ-REOHCLBHSA-N | [LogP]
-0.54 at 20℃ | [CAS DataBase Reference]
79-33-4(CAS DataBase Reference) | [NIST Chemistry Reference]
(s)-2-Hydroxypropanoic acid(79-33-4) | [EPA Substance Registry System]
79-33-4(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xi,C | [Risk Statements ]
R38:Irritating to the skin. R41:Risk of serious damage to eyes. R34:Causes burns. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S39:Wear eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S36:Wear suitable protective clothing . | [RIDADR ]
3261 | [WGK Germany ]
1
| [RTECS ]
OD2800000
| [F ]
3-10 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29181100 | [Toxicity]
LD50 intraperitoneal in mouse: 3194mg/kg |
Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o | [Definition]
ChEBI: An optically active form of lactic acid having (S)-configuration. | [General Description]
L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81). | [Flammability and Explosibility]
Notclassified | [Biochem/physiol Actions]
L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase. | [storage]
Store at 4°C, sealed storage, away from moisture | [Purification Methods]
Purify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.] |
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