| Identification | Back Directory | [Name]
MM-102 (trifluoroacetate) | [CAS]
1883545-52-5 | [Synonyms]
MM-102 (TFA)
HMTASE INHIBITOR IX (TFA)
MM-102 (trifluoroacetate)
1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide trifluoroacetate | [Molecular Formula]
C37H50F5N7O6 | [MDL Number]
MFCD29472272 | [MOL File]
1883545-52-5.mol | [Molecular Weight]
783.828 |
| Hazard Information | Back Directory | [Uses]
MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide. | [storage]
Store at -20°C | [References]
[1] Karatas H, et al. High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. J Am Chem Soc. 2013 Jan 16;135(2):669-682. DOI:10.1021/ja306028q |
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BOC Sciences
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https://www.bocsci.com |
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