| Identification | Back Directory | [Name]
25S-Inokosterone | [CAS]
19595-18-7 | [Synonyms]
25S-Inokosterone
Cholest-7-en-6-one, 2,3,14,20,22,26-hexahydroxy-, (2β,3β,5β,22R,25S)-
(2beta,3beta,5beta,22R,25S)-2,3,14,20,22,26-Hexahydroxycholest-7-en-6-one | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C27H44O7 | [MOL File]
19595-18-7.mol | [Molecular Weight]
480.63 |
| Chemical Properties | Back Directory | [Boiling point ]
713.179±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.280±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
14.125±0.70(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
25S-Inokosterone is a phytoecdysone in the roots of two same species of A. bidentata Blume and A. japonica Nakai, and two different species of C. capitata Moq and C. officinalis Kuan. 25S-Inokosterone has the potential for the LPS-induced acute kidney injury research[1][2]. | [References]
[1] Shengchao Wang, et al. Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway. Biomed Pharmacother DOI:10.1016/j.biopha.2020.110403
[2] Bing Tian Zhao, et al. High performance liquid chromatography used for quality control of Achyranthis Radix. Arch Pharm Res. 2012 Aug;35(8):1449-55. DOI:10.1007/s12272-012-0815-2
[3] K. Kim, et al.Phytoecdysones from the Roots of Achyranthes japonica Nakai and their Anti-atopy Activity. J Appl Biol Chem (2015) 58(1), 13-19. |
|
|