| Identification | More | [Name]
2-Bromothioanisole | [CAS]
19614-16-5 | [Synonyms]
1-BROMO-2-(METHYLTHIO)BENZENE
2-BROMOPHENYL METHYL SULFIDE
2-BROMOTHIOANISOLE
O-BROMOTHIOANISOLE
TIMTEC-BB SBB006566
1-Bromo-2-(methylsulfanyl)benzene
o-Bromo(methylthio)benzene
o-Bromophenyl methyl sulfide
Sulfide, o-bromophenyl methyl
Benzene, 1-bromo-2-(methylthio)-
2-(methylthio)bromobenzene
2-BROMOTHIOANISOLE/2-BROMOPHENYL METHYL SULPHIDE
2-BROMOTHIOANISOLE 97%
(2-bromophenyl)(methyl)sulfane
2-Bromothioanisole, 98+%
1-Methylthio-2-bromobenzene
2-(Methylthio)phenyl bromide
Methyl 2-bromophenyl sulfide | [EINECS(EC#)]
243-183-4 | [Molecular Formula]
C7H7BrS | [MDL Number]
MFCD00000066 | [Molecular Weight]
203.1 | [MOL File]
19614-16-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow liquid | [Melting point ]
-24 °C (lit.) | [Boiling point ]
145-146 °C/27 mmHg (lit.) | [density ]
1.522 g/mL at 25 °C(lit.) | [refractive index ]
1.632-1.634
| [Fp ]
>110°C | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Liquid | [color ]
Clear colorless to yellow | [Specific Gravity]
1.522 | [BRN ]
2243716 | [InChI]
InChI=1S/C7H7BrS/c1-9-7-5-3-2-4-6(7)8/h2-5H,1H3 | [InChIKey]
ALAQDUSTXPEHMH-UHFFFAOYSA-N | [SMILES]
C1(Br)=CC=CC=C1SC | [CAS DataBase Reference]
19614-16-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1-bromo-2-(methylthio)-(19614-16-5) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 3334 | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT, STENCH | [HS Code ]
29309090 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow liquid | [Uses]
2-Bromothioanisole has been used in the preparation of:
- thioether-methyleneborane (PhSCH2B (C6F5)2)2
- 1-dimesitylboryl-2-methylthio-benzene
| [Synthesis]
Under argon protection, sodium hydroxide (0.32 g, 7.9 mmol) was dissolved in ethanol (3.0 mL), and 2-bromothiophenol (1.0 g, 5.29 mmol) was added slowly and stirred for 30 min at room temperature. Subsequently, iodomethane (0.5 mL, 7.9 mmol) was added and the reaction continued to be stirred at room temperature for 3 hours. Upon completion of the reaction, the reaction was quenched by the addition of ice water (4.0 mL) and the reaction mixture was extracted with dichloromethane (10 mL x 3). The organic layers were combined, washed with saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by fast column chromatography (eluent: petroleum ether) to afford the target compound 2-bromothioanisole. | [References]
[1] Macromolecules, 2002, vol. 35, # 1, p. 67 - 78
[2] Tetrahedron Asymmetry, 2011, vol. 22, # 5, p. 575 - 579
[3] Patent: WO2015/86525, 2015, A1. Location in patent: Page/Page column 127
[4] Tetrahedron Asymmetry, 1999, vol. 10, # 6, p. 1051 - 1060
[5] Organic Letters, 2005, vol. 7, # 1, p. 143 - 145 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|