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10102-17-7

10102-17-7 Structure

10102-17-7 Structure
IdentificationMore
[Name]

Sodium thiosulfate pentahydrate
[CAS]

10102-17-7
[Synonyms]

ANTICHLOR
HYPO
SODIUM HYPOSULFATE, PENTAHYDRATE
SODIUM HYPOSULFITE
SODIUM HYPOSULFITE, PENTAHYDRATE
sodium subsulfite
SODIUM THIOCYANATE
SODIUM THIOSULFATE
SODIUM THIOSULFATE, 5-HYDRATE
SODIUM THIOSULFATE PENTAHYDRATE
SODIUM THIOSULPHATE
SODIUM THIOSULPHATE 5H2O
SODIUM THIOSULPHATE 5-HYDRATE
SODIUM THIOSULPHATE PENTAHYDRATE
ametox
nsc-45624
Sodiumthiosulfate,pentahydrat
Sulfothiorine
thiosulfuricacid(h2s2o3),disodiumsalt,pentahydrate
Thiosulfuricacid(H2S2O3)disodiumsalt,pentahydrate
[EINECS(EC#)]

231-867-5
[Molecular Formula]

H10Na2O8S2
[MDL Number]

MFCD00149186
[Molecular Weight]

248.18
[MOL File]

10102-17-7.mol
Chemical PropertiesBack Directory
[Appearance]

translucent crystals or white powder
[Melting point ]

48.5 °C
[Boiling point ]

100 C
[bulk density]

1000kg/m3
[density ]

1.01 g/mL at 25 °C
[refractive index ]

1.489
[storage temp. ]

Store at RT.
[solubility ]

H2O: 1 M at 20 °C, clear, colorless
[form ]

Solid
[color ]

White tranparent
[Specific Gravity]

1.729
[Odor]

Odorless
[PH]

6.0-7.5 (100g/l, H2O, 20℃)
[PH Range]

6 - 8.5
[Stability:]

Stable. Incompatible with strong acids, iodine, mercury.
[Water Solubility ]

680 g/L (20 ºC)
[Merck ]

14,8694
[Cosmetics Ingredients Functions]

REDUCING
[InChI]

1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
[InChIKey]

AKHNMLFCWUSKQB-UHFFFAOYSA-L
[SMILES]

O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=S
[LogP]

-0.428 (est)
[CAS DataBase Reference]

10102-17-7(CAS DataBase Reference)
[EPA Substance Registry System]

10102-17-7(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

1
[RTECS ]

WE6660000
[F ]

10
[TSCA ]

Yes
[HS Code ]

28323000
[Storage Class]

11 - Combustible Solids
[Toxicity]

LD50 orally in Rabbit: > 5000 mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->Hydrochloric acid-->Sulfuric acid-->Sodium carbonate-->Sulfur-->Sodium sulfite-->ZINC-->Sodium sulfide-->Activated carbon-->Sulfur dioxide-->Calcium oxide-->Sulphur-->Vanadium(V) oxide-->Potassium sodium tartrate-->BARIUM SULFIDE-->Sulphur Black 1
[Preparation Products]

Sodium thiosulfate-->Fomesafen-->2-(TRIFLUOROMETHYL)-4-ISOCYANATOPYRIDINE-->Molosultap-->5-bromo-1H-indazole-->S-METHYL-S-BENZYL SULFOXIMINE-->Bromoform-->Cartap-->2-QUINOXALINECARBALDEHYDE-->5-Bromopyridine-2-carbaldehyde-->5-Bromo-2-hydroxymethylpyridine-->5-BROMO-2-METHYLPYRIDINE N-OXIDE-->Chlorotrifluoroethylene-->(1S,2S,3R,5S)-(+)-2,3-Pinanediol-->Allicin
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Sodium thiosulfate pentahydrate(10102-17-7).msds
Hazard InformationBack Directory
[Chemical Properties]

Sodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.
[Chemical Properties]

translucent crystals or white powder
[Uses]

Titrimetry.
[Definition]

ChEBI: Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate.
[Production Methods]

On an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.
[Brand name]

Sulfactol (Sterling Winthrop).
[reaction suitability]

reaction type: Redox Reactions
[Pharmaceutical Applications]

Sodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.
[Safety]

Sodium thiosulfate is used in ophthalmic, intravenous, and oral pharmaceutical preparations. Apart from osmotic disturbances, sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and skin. Large oral doses have a cathartic action.
LD50 (IP, mouse) 5.6 g/kg
LD50 (IV, mouse) 2.4 g/kg
[storage]

Sodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.
[Purification Methods]

Crystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]
[Incompatibilities]

Sodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.
[Regulatory Status]

GRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Spectrum DetailBack Directory
[Spectrum Detail]

Sodium thiosulfate pentahydrate(10102-17-7)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Sodium thiosulfate pentahydrate, extra pure, 99+%(10102-17-7)
[Alfa Aesar]

Sodium thiosulfate pentahydrate, ACS, 99.5-101.0%(10102-17-7)
[Sigma Aldrich]

10102-17-7(sigmaaldrich)
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