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19741-14-1

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19741-14-1 Structure

19741-14-1 Structure
IdentificationBack Directory
[Name]

4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
[CAS]

19741-14-1
[Synonyms]

DAMPA
2,4-Apa
Nsc 131463
NSC 133723
NSC 131463 (DAMPA)
Deoxyaminopteroic acid
4-(((2,4-Diaminopteridin-6-yl)
DAMPA hemihydrochloride hydrate
N-10-Methyl-4-deoxy-4-aminopteroate
2,4-Diamino-N(10)-methylpteroic acid
4-AMino-4-deoxy-10-Methylpteroic Acid
4-amino-4-deoxy-n-10-methylpteroicacid
4-(N-(2,4-diamino-6-pteridinylme)-N-me-amino)benz
4[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO
diamino-6-pteridinylmethyl-N-methylaminobenzoic acid HCl
4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoic acid
p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid
4-{[(2,4-Diaminopteridin-6-yl)methyl]methylamino}benzoic acid
Benzoic acid, 4-[[(2,4-diaMino-6-pteridinyl)Methyl]MethylaMino]-
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
4-[[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino]benzenecarboxylic acid
4-(N-(2,4-DIAMINO-6-PTERIDINYLME)-N-ME-A MINO)BENZOIC ACID HEMI-HCL 2 H20,
4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]-benzoic acid hemihydro
4-[N-[(2,4-DiaMinopyriMido[4,5-b]pyrazin-6-yl)Methyl]-N- MethylaMino]benzoic Acid
bis(4-((2,4-diaminopteridin-6-ylmethyl)methylamino)benzoic) acid hydrochloride tetrahydrate
4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]benzoic acid hemihydrochloride dihydrate
[Molecular Formula]

C15H15N7O2
[MDL Number]

MFCD00075774
[MOL File]

19741-14-1.mol
[Molecular Weight]

325.33
Chemical PropertiesBack Directory
[Melting point ]

255 °C (dec.)(lit.)
[Boiling point ]

689.3±65.0 °C(Predicted)
[density ]

1.532
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

Aqueous Base, DMSO
[form ]

neat
[pka]

4.63±0.10(Predicted)
[color ]

Dark Yellow to Very Dark Brown
[Stability:]

Hygroscopic
[CAS DataBase Reference]

19741-14-1
Hazard InformationBack Directory
[Chemical Properties]

Brownish Yellow to Orange Solid
[Uses]

DAMPA is a Methotrexate (M260675) analog
[in vivo]

Methotrexate metabolite (8.6-10.1 mg/kg, 200 mg/m2, i.v., 15 minutes) has pharmacokinetic properties of rapid clearance and extensive metabolism in adult male Rhesus monkeys (Macaca mulatta) (8.0-15.9 kg), with an average clearance rate of 1.9 l/kg/h and an average terminal half-life of 51 minutes[1].

[storage]

Store at -20°C
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

43-52/53
[Safety Statements ]

36/37
[WGK Germany ]

3
Spectrum DetailBack Directory
[Spectrum Detail]

4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID(19741-14-1)1HNMR
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