| Identification | Back Directory | [Name]
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID | [CAS]
19741-14-1 | [Synonyms]
DAMPA
2,4-Apa
Nsc 131463
NSC 133723
NSC 131463 (DAMPA)
Deoxyaminopteroic acid
4-(((2,4-Diaminopteridin-6-yl)
DAMPA hemihydrochloride hydrate
N-10-Methyl-4-deoxy-4-aminopteroate
2,4-Diamino-N(10)-methylpteroic acid
4-AMino-4-deoxy-10-Methylpteroic Acid
4-amino-4-deoxy-n-10-methylpteroicacid
4-(N-(2,4-diamino-6-pteridinylme)-N-me-amino)benz
4[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO
diamino-6-pteridinylmethyl-N-methylaminobenzoic acid HCl
4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoic acid
p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid
4-{[(2,4-Diaminopteridin-6-yl)methyl]methylamino}benzoic acid
Benzoic acid, 4-[[(2,4-diaMino-6-pteridinyl)Methyl]MethylaMino]-
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
4-[[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino]benzenecarboxylic acid
4-(N-(2,4-DIAMINO-6-PTERIDINYLME)-N-ME-A MINO)BENZOIC ACID HEMI-HCL 2 H20,
4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]-benzoic acid hemihydro
4-[N-[(2,4-DiaMinopyriMido[4,5-b]pyrazin-6-yl)Methyl]-N-
MethylaMino]benzoic Acid
bis(4-((2,4-diaminopteridin-6-ylmethyl)methylamino)benzoic) acid hydrochloride tetrahydrate
4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino]benzoic acid hemihydrochloride dihydrate | [Molecular Formula]
C15H15N7O2 | [MDL Number]
MFCD00075774 | [MOL File]
19741-14-1.mol | [Molecular Weight]
325.33 |
| Chemical Properties | Back Directory | [Melting point ]
255 °C (dec.)(lit.)
| [Boiling point ]
689.3±65.0 °C(Predicted) | [density ]
1.532 | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Aqueous Base, DMSO | [form ]
neat | [pka]
4.63±0.10(Predicted) | [color ]
Dark Yellow to Very Dark Brown | [Stability:]
Hygroscopic | [CAS DataBase Reference]
19741-14-1 |
| Hazard Information | Back Directory | [Chemical Properties]
Brownish Yellow to Orange Solid | [Uses]
DAMPA is a Methotrexate (M260675) analog | [in vivo]
Methotrexate metabolite (8.6-10.1 mg/kg, 200 mg/m2, i.v., 15 minutes) has pharmacokinetic properties of rapid clearance and extensive metabolism in adult male Rhesus monkeys (Macaca mulatta) (8.0-15.9 kg), with an average clearance rate of 1.9 l/kg/h and an average terminal half-life of 51 minutes[1]. | [storage]
Store at -20°C |
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