| Identification | Back Directory | [Name]
Methotrexate α-Methyl Ester | [CAS]
66147-29-3 | [Synonyms]
Methotrexate Impurity I
Methotrexate EP Impurity I
Methotrexate α-Methyl Ester
JYFDQHNTJJOKAS-AWEZNQCLSA-N
Methotrexate-a-Methyl Ester
Methotrexate Impurity 9(EP-I)
Methotrexate-1-monomethyl ester
Methotrexate alpha-methyl ester
Methotrexate related compound I
Methotrexate α-Methyl Ester (Impurity I)
Methotrexate α-Methyl Ester (Impurity I)
Methotrexate Impurity 9（Methotrexate EP Impurity I）
Methotrexate EP Impurity I（Amethopterin EP Impurity I）
Methotrexate EP Impurity I (Methotrexate-1-Monomethyl Ester)
L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-methyl ester
(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
Methotrexate α-Methyl Ester，(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid | [Molecular Formula]
C21H24N8O5 | [MOL File]
66147-29-3.mol | [Molecular Weight]
468.47 |
| Chemical Properties | Back Directory | [density ]
1.459±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [pka]
4.429±0.10(predicted) | [color ]
Light Yellow to Dark Orange |
| Hazard Information | Back Directory | [Uses]
Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic. |
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