ChemicalBook--->CAS DataBase List--->66147-29-3

66147-29-3

66147-29-3 Structure

66147-29-3 Structure
IdentificationBack Directory
[Name]

Methotrexate α-Methyl Ester
[CAS]

66147-29-3
[Synonyms]

Methotrexate Impurity I
Methotrexate EP Impurity I
Methotrexate α-Methyl Ester
JYFDQHNTJJOKAS-AWEZNQCLSA-N
Methotrexate-a-Methyl Ester
Methotrexate Impurity 9(EP-I)
Methotrexate-1-monomethyl ester
Methotrexate alpha-methyl ester
Methotrexate related compound I
Methotrexate α-Methyl Ester (Impurity I)
Methotrexate α-Methyl Ester (Impurity I)
Methotrexate Impurity 9(Methotrexate EP Impurity I)
Methotrexate EP Impurity I(Amethopterin EP Impurity I)
Methotrexate EP Impurity I (Methotrexate-1-Monomethyl Ester)
L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-methyl ester
(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
Methotrexate α-Methyl Ester,(S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid
Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
[Molecular Formula]

C21H24N8O5
[MOL File]

66147-29-3.mol
[Molecular Weight]

468.47
Chemical PropertiesBack Directory
[density ]

1.459±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[solubility ]

Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
[form ]

Solid
[pka]

4.429±0.10(predicted)
[color ]

Light Yellow to Dark Orange
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H335-H315-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Uses]

Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
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