| Identification | More | [Name]
N-Acetyl-D-leucine | [CAS]
19764-30-8 | [Synonyms]
AC-D-LEUCINE
AC-D-LEU-OH
ACETYL-D-LEUCINE
N-ACETYL-D-LEUCINE
N-ALPHA-ACETYL-D-LEUCINE
n-acetyl-d-leucinesigmagr
N-Acetyle-D-Leucine
Ace-D-Leu-OH
N-ACETYL-L-LEUCINE:AC-D-LEU-OH
2-(Acetylamino)-4-methylpentanoic acid
N-ACETHY-D-LEUCINE
N-Ac-D-Leucine
2-Acetylamino-4-methylvaleric acid
N-Acetyl-2-isobutylglycine
D-2-Acetylamino-4-methylvaleric acid | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C8H15NO3 | [MDL Number]
MFCD00066069 | [Molecular Weight]
173.21 | [MOL File]
19764-30-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
176-177C | [Boiling point ]
369.7±25.0 °C(Predicted) | [density ]
1.069±0.06 g/cm3(Predicted) | [refractive index ]
23 ° (C=4, EtOH) | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
3.67±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m1/s1 | [InChIKey]
WXNXCEHXYPACJF-SSDOTTSWSA-N | [SMILES]
C(O)(=O)[C@@H](CC(C)C)NC(C)=O | [CAS DataBase Reference]
19764-30-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29241990 |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
N-Acetyl-D-leucine may be used with other D-aminoacylated amino acids as a substrate for the identification, differentiation and characterization of D-aminoacylase(s)/amidohydrolase(s). | [Definition]
ChEBI: N-acetyl-D-leucine is the N-acetyl derivative of D-leucine. It is a N-acetyl-D-amino acid and a D-leucine derivative. It is a conjugate acid of a N-acetyl-D-leucinate. It is an enantiomer of a N-acetyl-L-leucine. | [Biological Activity]
N-Acetyl-D-leucine is a substrate for D-aminoacylase from Alcaligenes xylosoxydans subsp. xylosoxydans A-6. N-Acetyl-D-leucine is used to help differentiate members of the amidohydrolase enzyme superfamily. It is a preferred substrate of Gox1177 from Gluconobacter oxidans. | [in vivo]
N-Acetyl-R-leucine (24 mg per rat; i.v.; once a day) has no significant effect on the compensation of nystagmus and postural imbalance scores in rats[4].
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