Identification | Back Directory | [Name]
L-771688 | [CAS]
200050-59-5 | [Synonyms]
L-771688 5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester, (6S)- | [Molecular Formula]
C28H33F2N5O5 | [MDL Number]
MFCD31544398 | [MOL File]
200050-59-5.mol | [Molecular Weight]
557.59 |
Chemical Properties | Back Directory | [density ]
1.274±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Oil | [pka]
10.90±0.70(Predicted) | [color ]
Colorless to light yellow |
Hazard Information | Back Directory | [Uses]
L-771688 is a highly selective α1A-Adrenoceptor antagonist with a Ki of 0.43±0.02 nM. | [IC 50]
α adrenergic receptor | [References]
[1] Chang RS, et al. In vitro studies on L-771,688 (SNAP 6383), a new potent and selective alpha1A-adrenoceptor antagonist. Eur J Pharmacol. 2000 Dec 15;409(3):301-12. DOI:10.1016/s0014-2999(00)00854-2 |
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MedChemExpress
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