| Identification | Back Directory | [Name]
(S)-3,4-DCPG | [CAS]
201730-11-2 | [Synonyms]
DCPG
4-DCPG
UBP1109
(S)-3,4-DCPG
(S)-3,4-DCPG USP/EP/BP
(S)-3,4-DICARBOXYPHENYLGLYCINE
1,2-Benzenedicarboxylic acid, 4-[(S)-aminocarboxymethyl]- | [Molecular Formula]
C10H9NO6 | [MDL Number]
MFCD03453633 | [MOL File]
201730-11-2.mol | [Molecular Weight]
239.18 |
| Chemical Properties | Back Directory | [Boiling point ]
531.0±50.0 °C(Predicted) | [density ]
1.634±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 33 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
Powder | [pka]
1.59±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water | [InChI]
InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1 | [InChIKey]
IJVMOGKBEVRBPP-ZETCQYMHSA-N | [SMILES]
C1(C(O)=O)=CC=C([C@H](N)C(O)=O)C=C1C(O)=O |
| Hazard Information | Back Directory | [Uses]
(S)-3,4-DCPG is a potent and selective mGluR-8a agonist. | [Biological Activity]
Potent, selective mGlu 8a agonist (EC 50 = 31 nM). Displays > 100-fold selectivity over mGlu 1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo . Also potent anticonvulsant in mice in vivo . | [IC 50]
hmGluR8a: 31 nM (EC50) | [storage]
Desiccate at RT |
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821-50328103-801 18930552037 |
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Energy Chemical
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cjbscvictory
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https://www.weikeqi-biotech.com/ |
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