| Identification | Back Directory | [Name]
7-METHYLGUANOSINE | [CAS]
20244-86-4 | [Synonyms]
N7-Me-Gr
Aids024328
Aids-024328
N7-Methylguanosine
N(7)-Methylguanosine
7-METHYLGUANOSINE USP/EP/BP
2-amino-6,9-dihydro-7-methyl-6-oxo-9-1H-Purinium
2-Amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purin-7-ium
1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-.beta.-D-ribofuranosyl-
2-Amino-6-oxo-7-methyl-9-(β-D-ribofuranosyl)-1,6-dihydro-9H-purine-7-ium
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-7-methyl-6-purin-9-iumolate
2-aMino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-7-Methyl-6-oxo-6,7-dihydro-1H-purin-9-iuM | [Molecular Formula]
C11H15N5O5 | [MDL Number]
MFCD00038418 | [MOL File]
20244-86-4.mol | [Molecular Weight]
297.27 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
0.1 M HCl: 10 mg/ml; DMSO: 10 mg/ml | [form ]
A crystalline solid | [color ]
White to light yellow | [PH]
7.3 | [biological source]
synthetic | [Water Solubility ]
water: 50mg/mL, clear to hazy, colorless to faintly yellow | [λmax]
257 (pH 3)；258，281 (pH 7)；282 (pH 9) | [BRN ]
3713683 | [Stability:]
Hygroscopic | [InChI]
InChI=1/C11H17N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h4,6-7,10,17-19H,2-3H2,1H3,(H3,12,13,14,20)/t4-,6-,7-,10-/s3 | [InChIKey]
OGHAROSJZRTIOK-KQYNXXCUSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N(C)C2)[C@H](O)[C@@H]1O |&1:2,4,17,19,r| |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
7-Methylguanosine has been used in the removal of residual phosphates from pre rigor solution, phosphate mop system and phosphorous standard solution. | [Definition]
ChEBI: A positively charged methylguanosine in which a single methyl substituent is located at position 7. | [General Description]
7-Methylguanosine structure is also referred to as a cap. It is located on the 5′ end of the cytoplasmic mRNA. | [Biochem/physiol Actions]
7-Methylguanosine is involved in the processing of a cap-dependent translational process of mRNA. It is also involved in protecting the mRNA from degradation due to ribonucleases and mediate nuclear export. 7-Methylguanosine also permits the recruitment of ribosome. |
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