| Identification | More | [Name]
5-METHYLCYTOSINE | [CAS]
554-01-8 | [Synonyms]
5-METHYLCYTOSINE
4-Amino-5-methyl-2-pyrimidinol
Cytosine, 5-methyl-
5-Methylcytosine,>96%
2(1H)-Pyrimidinone, 4-amino-5-methyl-(9CI)
4-amino-5-methyl-3H-pyrimidin-2-one
2(1H)-Pyrimidinone, 6-amino-5-methyl-
2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine
2(1H)-Oxo-4-amino-5-methylpyrimidine
2-Hydroxy-4-amino-5-methylpyrimidine
4-Amino-5-methyl-1,2-dihydropyrimidine-2-one
4-Amino-5-methylpyrimidin-2(1H)-one | [EINECS(EC#)]
209-058-3 | [Molecular Formula]
C5H7N3O | [MDL Number]
MFCD00233537 | [Molecular Weight]
125.13 | [MOL File]
554-01-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystals in prisms from water. | [Melting point ]
270°C (rough estimate) | [Boiling point ]
232.57°C (rough estimate) | [density ]
1.2602 (rough estimate) | [refractive index ]
1.6510 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Methanol (Sparingly, Heated) | [form ]
Crystalline | [pka]
9.05±0.10(Predicted) | [color ]
White to Off-White | [Water Solubility ]
Soluble in water. | [Merck ]
14,6050 | [InChI]
InChI=1S/C5H7N3O/c1-3-2-7-5(9)8-4(3)6/h2H,1H3,(H3,6,7,8,9) | [InChIKey]
LRSASMSXMSNRBT-UHFFFAOYSA-N | [SMILES]
C1(=O)NC(N)=C(C)C=N1 | [CAS DataBase Reference]
554-01-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystals in prisms from water. | [Uses]
5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde. | [Definition]
ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position. | [IC 50]
Microbial Metabolite; Human Endogenous Metabolite | [Purification Methods]
Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.] |
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| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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