| Identification | Back Directory | [Name]
mPEG12-OH | [CAS]
2050595-03-2 | [Synonyms]
3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol | [Molecular Formula]
C25H52O13 | [MDL Number]
MFCD06797088 | [MOL File]
2050595-03-2.mol | [Molecular Weight]
560.67 |
| Hazard Information | Back Directory | [Uses]
m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. | [IC 50]
PEGs; Non-cleavable Linker | [References]
[1] Kachbi-Khelfallah S, et al. Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates. Beilstein J Org Chem. 2016 Jul 4;12:1366-71. DOI:10.3762/bjoc.12.130
[2] Hamura, Mika, et al. Branched monodispersed polyethylene glycol, intermediate, and method for producing same. WO 2019181984 A1. |
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