ChemicalBook--->CAS DataBase List--->2135793-73-4

2135793-73-4

2135793-73-4 Structure

2135793-73-4 Structure
IdentificationBack Directory
[Name]

MPEG11-CH2CH2COOH
[CAS]

2135793-73-4
[Synonyms]

mPEG11-COOH
m-dPEG12-acid
MPEG11-CH2CH2COOH
Methyl-PEG12-Carboxylic Acid
4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic Acid
[Molecular Formula]

C26H52O14
[MDL Number]

MFCD08274611
[MOL File]

2135793-73-4.mol
[Molecular Weight]

588.68
Chemical PropertiesBack Directory
[Boiling point ]

628.8±55.0 °C(Predicted)
[density ]

1.113±0.06 g/cm3(Predicted)
[storage temp. ]

Storage temp. 2-8°C
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[form ]

liquid
[pka]

4.28±0.10(Predicted)
[color ]

Colourless
[InChI]

InChI=1S/C26H52O14/c1-29-4-5-31-8-9-33-12-13-35-16-17-37-20-21-39-24-25-40-23-22-38-19-18-36-15-14-34-11-10-32-7-6-30-3-2-26(27)28/h2-25H2,1H3,(H,27,28)
[InChIKey]

JMAKFNFKUHXFBH-UHFFFAOYSA-N
[SMILES]

C(O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P362+P364
[HS Code ]

2918999090
Questions And AnswerBack Directory
[Purity]

>98%
Hazard InformationBack Directory
[Description]

m-PEG12-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

MeO-?PEG(12)?-?COOH is used in the preparation of fishbone-?like polymer brushes with potential applications in the production of smart materials and biosensors.
[General Description]

MPEG11-CH2CH2COOH (CAS 2135793-73-4) is a high-purity, monodisperse PEG-based PROTAC linker. It has a molecular weight of 588.68 and appears as a colourless to pale yellow viscous liquid or a low-melting-point waxy solid at room temperature. This substance is also known as m-PEG12-acid, mPEG11-propionic acid and mPEG11-COOH. It should be noted that m-PEG12-acid usually refers to a polydisperse polymer with CAS number 125220-94-2. Care should be taken to distinguish between the two when purchasing.
[IC 50]

PEGs
Spectrum DetailBack Directory
[Spectrum Detail]

MPEG11-CH2CH2COOH(2135793-73-4)1HNMR
MPEG11-CH2CH2COOH(2135793-73-4)13CNMR
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