| Identification | Back Directory | [Name]
MPEG12-N3 | [CAS]
2170098-29-8 | [Synonyms]
MPEG12-N3
mPEG12-N3/2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontane, 37-azido- | [Molecular Formula]
C25H51N3O12 | [MDL Number]
MFCD13184959 | [MOL File]
2170098-29-8.mol | [Molecular Weight]
585.69 |
| Hazard Information | Back Directory | [Uses]
m-PEG12-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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