| Identification | Back Directory | [Name]
MPEG12-N3 | [CAS]
2170098-29-8 | [Synonyms]
MPEG12-N3
mPEG12-N3/2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontane, 37-azido- | [Molecular Formula]
C25H51N3O12 | [MDL Number]
MFCD13184959 | [MOL File]
2170098-29-8.mol | [Molecular Weight]
585.69 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C, sealed storage, away from moisture | [form ]
clear liquid | [color ]
Colorless to Light yellow | [InChI]
InChI=1S/C25H51N3O12/c1-29-4-5-31-8-9-33-12-13-35-16-17-37-20-21-39-24-25-40-23-22-38-19-18-36-15-14-34-11-10-32-7-6-30-3-2-27-28-26/h2-25H2,1H3 | [InChIKey]
FXVJBKLBTILMNA-UHFFFAOYSA-N | [SMILES]
C(COCCOCCOCCOCCOCCN=[N+]=[N-])OCCOCCOCCOCCOCCOCCOC |
| Hazard Information | Back Directory | [Uses]
m-PEG12-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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