| Identification | Back Directory | [Name]
Propargyl-PEG10-alcohol | [CAS]
2055022-35-8 | [Synonyms]
2055022-35-8
CAS_2055022-35-8
Propargyl-PEG9-OH
Propargyl-PEG10-OH
Propargyl-PEG10-alcohol
3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-ol | [Molecular Formula]
C21H40O10 | [MDL Number]
MFCD28976698 | [MOL File]
2055022-35-8.mol | [Molecular Weight]
452.54 |
| Chemical Properties | Back Directory | [Boiling point ]
518.0±45.0 °C(Predicted) | [density ]
1.093±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [pka]
14.36±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG10-alcohol is a heterobifunctional PEG linker which enables Click Chemistry reactions with azide-bearing biomolecules; copper catalyst is needed. The hydrophilic PEG units increase aqueous solubility. | [Uses]
Propargyl-PEG9-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG9-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1. |
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