2055896-77-8

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2055896-77-8 Structure

Identification	Back Directory
[Name] MC-Val-Cit-PAB-Auristatin E
[CAS] 2055896-77-8
[Synonyms] MC-Val-Cit-PAB-Auristatin E
[Molecular Formula] C68H108N11O13+
[MDL Number] MFCD32197310
[MOL File] 2055896-77-8.mol
[Molecular Weight] 1287.68

Hazard Information	Back Directory
[Uses] MC-Val-Cit-PAB-Auristatin E is a agent-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.
[IC 50] Auristatin
[References] [1] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635

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