| Identification | Back Directory | [Name]
L-Phenylalanine, N-methyl-N-[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl- | [CAS]
863971-56-6 | [Synonyms]
L-Phenylalanine, N-methyl-N-[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl- | [Molecular Formula]
C58H92N10O13 | [MDL Number]
MFCD28398145 | [MOL File]
863971-56-6.mol | [Molecular Weight]
1137.43 |
| Hazard Information | Back Directory | [Uses]
Val-Cit-PAB-MMAF is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAF contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin polymerization inhibitor MMAF (HY-15579)[1] | [IC 50]
Auristatin | [References]
[1] Svetlana Doronina, et al. Monomethylvaline compounds capable of conjugation to ligands. US20050238649A1. |
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