| Chemical Properties | Back Directory | [Boiling point ]
629.7±55.0 °C(Predicted) | [density ]
1.06±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
14.31±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Calcitriol Derivatives is a vitamin D3 analog. v | [storage]
Store at -20°C | [References]
[1] Barrera D, Noyola-Martínez N, Avila E, Halhali A, Larrea F, Díaz L. Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions. Cytokine. 2012 Mar;57(3):316-21. DOI:10.1016/j.cyto.2011.11.020
[2] Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Am J Nephrol. 2012;35(1):58-68. DOI:10.1159/000334626
[3] Michalak K, Wicha J. Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione. J Org Chem. 2011 Aug 19;76(16):6906-11. DOI:10.1021/jo201083w
[4] Moorthi RN, Kandula P, Moe SM. Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question. Curr Opin Nephrol Hypertens. 2011 Jul;20(4):354-9. DOI:10.1097/MNH.0b013e3283470450
[5] Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle. 2010 Aug 1;9(15):3022-9. DOI:10.4161/cc.9.15.12381 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|