| Identification | Back Directory | [Name]
APHS | [CAS]
209125-28-0 | [Synonyms]
APHS
Aids081123
Aids-081123
2-(2-HEPTYNYLTHIO)-PHENOL ACETATE
PHENOL 2-(2-HEPTYNYLTHIO)-ACETATE
o-(Acetophenyl)hept-2-ynyl sulphide
o-(Acetoxyphenyl)hept-2-ynyl sulphide
Phenol, 2-(2-heptyn-1-ylthio)-, 1-acetate | [Molecular Formula]
C15H18O2S | [MDL Number]
MFCD02183594 | [MOL File]
209125-28-0.mol | [Molecular Weight]
262.37 |
| Chemical Properties | Back Directory | [Boiling point ]
363.286±27.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.103±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil. | [color ]
Clear Colorless to Light Yellow |
| Hazard Information | Back Directory | [Uses]
An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1. | [Uses]
An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
ChemeGen
|
| Telephone: |
18818260767 |
| Website: |
https://www.chemegen.com |
|