| Identification | Back Directory | [Name]
DBCO-PEG3-amine | [CAS]
2093409-57-3 | [Synonyms]
DBCO-PEG3-amine DBCO-PEG3-amine,DBCO-PEG3-NH2 Dibenz[b,f]azocine-5(6H)-butanamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-11,12-didehydro-γ-oxo- | [Molecular Formula]
C27H33N3O5 | [MDL Number]
MFCD32641904 | [MOL File]
2093409-57-3.mol | [Molecular Weight]
479.58 |
| Hazard Information | Back Directory | [Uses]
DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG3-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
csynbio
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| Tel: |
15051477682 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1949820/0_EN.htm |
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