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2566404-76-8

2566404-76-8 Structure

2566404-76-8 Structure
IdentificationBack Directory
[Name]

DBCO-PEG3-OH
[CAS]

2566404-76-8
[Synonyms]

DBCO-PEG3-OH
[Molecular Formula]

C27H32N2O6
[MOL File]

2566404-76-8.mol
[Molecular Weight]

480.56
Chemical PropertiesBack Directory
[Boiling point ]

777.1±60.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[pka]

14.36±0.10(Predicted)
[InChI]

InChI=1S/C27H32N2O6/c30-14-16-34-18-20-35-19-17-33-15-13-28-26(31)11-12-27(32)29-21-24-7-2-1-5-22(24)9-10-23-6-3-4-8-25(23)29/h1-8,30H,11-21H2,(H,28,31)
[InChIKey]

ALXJBBJGKMRACK-UHFFFAOYSA-N
[SMILES]

C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCOCCO
Hazard InformationBack Directory
[Description]

Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions.
[Uses]

Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].
[References]

[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910
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