| Identification | Back Directory | [Name]
N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt | [CAS]
209518-16-1 | [Synonyms]
madb
MADB ROBIOT
Sodium 4,4'-((3,5-dimethylphenyl)
N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt
MADB (N,N-BIS(4-SULFOBUTYL)-3,5-DIMETHYLANILINE DISODIUM SALT)
4-[3,5-dimethyl-N-(4-sulfonatobutyl)anilino]butane-1-sulfonate
SodiuM 4,4'-((3,5-diMethylphenyl)azanediyl)bis(butane-1-sulfonate)
4,4'-[(3,5-Dimethylphenyl)imino]bis-1-butanesulfonic acid disodium salt | [Molecular Formula]
C16H25NNa2O6S2 | [MDL Number]
MFCD09038767 | [MOL File]
209518-16-1.mol | [Molecular Weight]
437.48 |
| Chemical Properties | Back Directory | [InChI]
InChI=1S/C16H27NO6S2.Na.H/c1-14-11-15(2)13-16(12-14)17(7-3-5-9-24(18,19)20)8-4-6-10-25(21,22)23;;/h11-13H,3-10H2,1-2H3,(H,18,19,20)(H,21,22,23);; | [InChIKey]
HNZNYERWZSSAOO-UHFFFAOYSA-N | [SMILES]
N(C1C=C(C)C=C(C)C=1)(CCCCS(O)(=O)=O)CCCCS(O)(=O)=O.[NaH] |
| Hazard Information | Back Directory | [Uses]
N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt (MADB) is an important colour-forming reagent used in the quantitative detection of glucose. The function of MADB is to undergo an oxidative coupling reaction with 4-aminoantipyrine (4-AAP) in the presence of hydrogen peroxide and horseradish peroxidase (HRP), producing a coloured oxidised complex [1–3]. | [References]
[1] Jang, H., Oh, J., Ki, H., Kim, M.-G. (2020). Paper-based 1,5-anhydroglucitol quantification using enzyme-based glucose elimination†. Analyst, 17, 5740–5743. https://doi.org/10.1039/D0AN00905A
[2] Gyeo-Re Han. (2021). Reagent Filming for Universal Point-of-Care Diagnostics. Small Methods, 5 12. https://doi.org/10.1002/smtd.202100645
[3] Jie Cheng, Jinhong G., Jiuchuan Guo. (2023). A Low-cost Creatinine Biosensor by Differential Optical Signal Readout for the Whole Blood Analysis. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2023, 1–4. https://doi.org/10.1109/EMBC40787.2023.10341195
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