| Chemical Properties | Back Directory | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 150 mg/mL (165.93 mM) | [form ]
Solid | [pka]
10.68±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology[1]. | [IC 50]
BRD9: 13.5 nM (IC50); BRD4: 3.78 μM (IC50); CRBN-DDB1: 48.9 nM (IC50) | [storage]
Store at -20°C | [References]
[1] Remillard D, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743. DOI:10.1002/anie.201611281 |
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MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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