| Identification | Back Directory | [Name]
PROTAC CRBN Degrader-1 | [CAS]
2358775-70-7 | [Synonyms]
CRBN PROTAC?14a
PROTAC CRBN Degrader-1 | [Molecular Formula]
C53H72N8O13S | [MDL Number]
MFCD32197292 | [Molecular Weight]
1061.25 |
| Chemical Properties | Back Directory | [Boiling point ]
1241.2±65.0 °C(Predicted) | [density ]
1.294±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 200 mg/mL (188.46 mM) | [form ]
Solid | [pka]
10.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
CRBN PROTAC? 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation. | [storage]
Store at -20°C |
|
|