ChemicalBook--->CAS DataBase List--->2131798-13-3

2131798-13-3

Request For Quotation
2131798-13-3 Structure

2131798-13-3 Structure
IdentificationBack Directory
[Name]

GSK-656
[CAS]

2131798-13-3
[Synonyms]

GSK-656
GSK656 HCl
GSK-3036656
GSK656,GSK-656
GSK656 HCl (GSK3036656, GSK070)
[Molecular Formula]

C10H14BCl2NO4
[MDL Number]

MFCD31657361
[MOL File]

2131798-13-3.mol
[Molecular Weight]

293.94
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:67.5(Max Conc. mg/mL);229.64(Max Conc. mM)
[form ]

Solid
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)Skull and Crossbones (GHS06)
GHS08,GHS06
[Signal word ]

Danger
[Hazard statements ]

H373-H301
[Precautionary statements ]

P260-P314-P501-P264-P270-P301+P310-P321-P330-P405-P501
Hazard InformationBack Directory
[Uses]

Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM.
[in vivo]

Ganfeborole hydrochloride shows potent antitubercular activity in mice infected with M. tuberculosis H37Rv, with ED99 of 0.4 mg/kg[1].

[References]

[1] Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026. DOI:10.1021/acs.jmedchem.7b00631
2131798-13-3 suppliers list
Company Name: ShangHai Biochempartner Co.,Ltd  
Telephone: 177-54423994 17754423994
Website: www.biochempartner.com
Company Name: Twochem Co.Ltd.  
Telephone: 021-58111628 15800915896
Website: cn.twochem.com
Company Name: Shanghai Anyinuo Biomedical Technology Co., Ltd.  
Telephone: 021-34625901
Website: https://www.aynchem.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Telephone: 15911056312
Website: www.bio-fount.com
Company Name: Tianjin Kaifu Pharmaceutical Technology Co., Ltd.  
Telephone: 18081075745
Website: www.chemicalbook.com/ShowSupplierProductsList31177/0_EN.htm
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Telephone: 18818260767
Website: http://www.chemegen.com
Company Name: Shanghai hongqu biomedical technology co. LTD  
Telephone: 88888888888
Website: www.chemicalbook.com/ShowSupplierProductsList873228/0_EN.htm
Company Name: Chunchuang (Wuhan) Technology Co., Ltd  
Telephone: 15727060112
Website: www.chemicalbook.com/showsupplierproductslist1427518/0_en.htm
Company Name: Wuhan Topule  
Telephone: +86-02787215551 19945035818
Website: http://www.topule.com/
Company Name: Abmole Bioscience Inc.  
Telephone: 19821158099
Website: www.abmole.cn/
Company Name: Hubei Kele Fine Chemical Co., Ltd  
Telephone: 027-59101668 19945030958
Website: www.kerle.cn
Company Name: Kaifeng Mingren Pharmaceutical Co.,LTD  
Telephone: 0371-65741762
Website: www.kfmryy.com/
Company Name: InvivoChem  
Telephone: 13549236410
Website: https://www.invivochem.cn/
Company Name: Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.  
Telephone: +86-027-59232304 15387063101
Website: https://www.yingnor.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Telephone: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Telephone: 025-85560043 15850508050
Website: http://www.synzest.com
Company Name: Shanghai Zunlijia Life Technology Co., Ltd  
Telephone: 021-34045219 13062664914
Website: www.zunlijia.com
Tags:2131798-13-3 Related Product Information
20350-15-6 56-65-5 1405-10-3 18883-66-4 50-28-2 62996-74-1