Identification | Back Directory | [Name]
(Z)-(R)-N-((2-Hydroxy-1-methyl)ethyl)-9-octadecenamide | [CAS]
213182-22-0 | [Synonyms]
AM3102 KDS-5104 AM3102 Exclusive Methyl oleoylethanolamide (R)-N-(1-Hydroxypropan-2-yl)oleamide (Z)-N-[(2R)-1-hydroxypropan-2-yl]octadec-9-enamide (Z)-(R)-N-((2-HYDROXY-1-METHYL)ETHYL)-9-OCTADECENAMIDE (9Z)-N-[(1R)-2-Hydroxy-1-methylethyl]-9-octadecenamide (Z)-(R)-9-Octadecenamide,N-((2-hydroxy-1-methyl) ethyl) 9-Octadecenamide, N-[(1R)-2-hydroxy-1-methylethyl]-, (9Z)- | [Molecular Formula]
C21H41NO2 | [MOL File]
213182-22-0.mol | [Molecular Weight]
339.56 |
Chemical Properties | Back Directory | [Melting point ]
39-40 °C | [Boiling point ]
503.6±43.0 °C(Predicted) | [density ]
0.911 | [solubility ]
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
14.51±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
AM3102 is an oleoylethanolamide (OEA) analog. AM3102 is an endogenous high-affinity PPAR-alpha agonist. AM3102 resists enzymatic hydrolysis, activates PPAR-alpha with high potency in vitro, and persistently reduces feeding when administered in vivo either parenterally or orally[1]. | [Definition]
ChEBI: AM3102 is a carboximidic acid. | [References]
[1] Astarita G, et al. Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties. J Pharmacol Exp Ther. 2006;318(2):563-570. DOI:10.1124/jpet.106.105221 |
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