| Identification | Back Directory | [Name]
Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester | [CAS]
2148295-91-2 | [Synonyms]
(2,3,4,5,6-pentafluorophenyl) 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoate
Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester | [Molecular Formula]
C16H15F5O5 | [MDL Number]
MFCD29049370 | [MOL File]
2148295-91-2.mol | [Molecular Weight]
382.28 |
| Hazard Information | Back Directory | [Uses]
Propargyl-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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