ChemicalBook--->CAS DataBase List--->2149-70-4

2149-70-4

2149-70-4 Structure

2149-70-4 Structure
IdentificationMore
[Name]

N'-Nitro-L-arginine
[CAS]

2149-70-4
[Synonyms]

ARGININE(NO2)-OH
ARG(NO2)
H-ARG(NO2)-OH
H-ARG(NO2)-OME
H-L-ARG(NO2)-OH
L-ARGININE(NITRO)
L-NA
L-NG-NITROARGININE
L-NITROARGININE
L-NNA
L-NO2ARG
L-NOARG
N5-[IMINO(NITROAMINO)METHYL]-L-ORNITHINE
N5-[NITROAMIDINO]-L-2,5-DIAMINOPENTANOIC ACID
NG-NITRO-L-ARGININE
NG-NO2-L-ARG
NITRO-L-ARGININE
N-NITRO-L-ARGININE
N-OMEGA-NITRO-L-ARGININE
S(+)-N5-[IMINO(NITROAMINO)METHYL]-ORNITHINE
[EINECS(EC#)]

218-418-9
[Molecular Formula]

C6H13N5O4
[MDL Number]

MFCD00007033
[Molecular Weight]

219.2
[MOL File]

2149-70-4.mol
Chemical PropertiesBack Directory
[Appearance]

WHITE TO OFF-WHITE POWDER
[Melting point ]

257 °C (dec.)(lit.)
[alpha ]

23.5 º (c=4, 2N HCl 24 ºC)
[Boiling point ]

360°C (rough estimate)
[density ]

1.4177 (rough estimate)
[refractive index ]

1.8000 (estimate)
[RTECS ]

RM2982100
[storage temp. ]

Store at RT.
[solubility ]

DMF: <50 μg/ml; DMSO: <50 μg/ml; Ethanol: <50 μg/ml; PBS pH 7.2: 1 mg/ml
[form ]

powder to crystal
[pka]

2.49±0.24(Predicted)
[color ]

White to Almost white
[biological source]

synthetic
[Water Solubility ]

Soluble to 5 mM in water
[BRN ]

1728914
[InChIKey]

MRAUNPAHJZDYCK-BYPYZUCNSA-N
[CAS DataBase Reference]

2149-70-4(CAS DataBase Reference)
[EPA Substance Registry System]

2149-70-4(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[TSCA ]

Yes
[HazardClass ]

IRRITANT
[HS Code ]

29299090
Hazard InformationBack Directory
[Hazard]

A reproductive hazard.
[Chemical Properties]

WHITE TO OFF-WHITE POWDER
[Uses]

Nω-Nitro-L-arginine is an inhibitor for nitric oxide synthase and is used in the study of bacterium to determine effective treatments. Used in the study of MRSA (Methicillin-Resistant Staphylococcus Aureus).
[Definition]

ChEBI: N(gamma)-nitro-L-arginine is an L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group. It is a L-arginine derivative, a N-nitro compound, a member of guanidines and a non-proteinogenic L-alpha-amino acid.
[Biological Activity]

NO synthase inhibitor.
[Biochem/physiol Actions]

Nω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia.
[Safety Profile]

Experimental reproductiveeffects. When heated to decomposition it emits toxicvapors of NOx.
Spectrum DetailBack Directory
[Spectrum Detail]

N'-Nitro-L-arginine(2149-70-4)MS
N'-Nitro-L-arginine(2149-70-4)IR1
N'-Nitro-L-arginine(2149-70-4)IR2
N'-Nitro-L-arginine(2149-70-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

2149-70-4(sigmaaldrich)
[TCI AMERICA]

Nomega-Nitro-L-arginine,>98.0%(T)(2149-70-4)
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