ChemicalBook--->CAS DataBase List--->21516-68-7

21516-68-7

21516-68-7 Structure

21516-68-7 Structure
IdentificationBack Directory
[Name]

MONASCIN
[CAS]

21516-68-7
[Synonyms]

MONASCIN
Ccris 9138
Monascoflavin
Monascin >=97.0% (HPLC)
(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione
(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-
[Molecular Formula]

C21H26O5
[MDL Number]

MFCD09260177
[MOL File]

21516-68-7.mol
[Molecular Weight]

358.43
Chemical PropertiesBack Directory
[Melting point ]

145 °C
[Boiling point ]

574.6±50.0 °C(Predicted)
[density ]

1.18±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

10.59±0.60(Predicted)
[BRN ]

51355
[InChIKey]

XXKNHBAFFJINCK-RVEJDSBJSA-N
Safety DataBack Directory
[WGK Germany ]

2
Hazard InformationBack Directory
[Uses]

Monascin is an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration.
[Definition]

ChEBI: An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of car inogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.
[Biochem/physiol Actions]

Monascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors.
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