ChemicalBook--->CAS DataBase List--->6205-14-7

6205-14-7

6205-14-7 Structure

6205-14-7 Structure
IdentificationMore
[Name]

Hydroxycitric acid
[CAS]

6205-14-7
[Synonyms]

TRIPOTASSIUM-2-HYDROXYCITRATE
Tripotassium-2-Hydroxycditracte
HAC
HYDROXYCITRICACIDANDITSTRISODIUMSALT
HYDROXYCITRIC ACID hplc
1,2-Dihydroxy-1,2,3-propanetricarboxylic acid
Hydroxycitric acid
Tripotassium-2-Hydroxycitrate(KHCA)
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C6H8O8
[MDL Number]

MFCD07787355
[Molecular Weight]

208.12
[MOL File]

6205-14-7.mol
Questions And AnswerBack Directory
[Synthesis]

This synthetic method uses citric acid as a raw material, which is dehydrated to produce aconitic acid, and then oxidized to produce hydroxycitric acid. The optimized processes for aconitic acid and hydroxycitric acid were studied separately. The optimized process conditions for aconitic acid were: 1 mol of hydroxycitric acid reacted with 270 mol of 56% sulfuric acid at 140℃ for 7 h to obtain refined aconitic acid with a melting point of 186℃. Waste acid and undecomposed citric acid were recycled, achieving a citric acid recovery rate of 28% and a concentrated sulfuric acid recovery rate of 65%. The optimized process conditions for hydroxycitric acid were: a ratio of n-oxidant to n-aconitic acid of 2:1, a reaction time of 16 h, and a reaction temperature of 50℃ to obtain hydroxycitric acid with a product yield of approximately 80%.
Process diagram for the synthesis of hydroxycitric acid
Figure 2: Process diagram for the synthesis of hydroxycitric acid
Chemical PropertiesBack Directory
[Boiling point ]

393.3±42.0 °C(Predicted)
[density ]

1.947±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

Aqueous acid: 10 mg/ml,DMF: Slightly soluble
[form ]

A crystalline solid
[pka]

2.90±0.28(Predicted)
[CAS DataBase Reference]

6205-14-7(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
Hazard InformationBack Directory
[Uses]

Hydroxycitric Acid is used in preparation method and application of photocurable resin based on organic polyacid.
[Application]

Hydroxycitric acid is the sodium salt of a plant metabolite that is found in beans and has been shown to have anti-inflammatory effects. It has been shown to inhibit the enzyme activities of lipoxygenase and cyclooxygenase as well as the toxicity of metal hydroxides in vitro.It also inhibits protein synthesis and induces apoptosis in k562 cells. 
[Definition]

ChEBI: Hydroxycitric acid is a carbonyl compound.
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