| Identification | Back Directory | [Name]
WY-135 | [CAS]
2163060-83-9 | [Synonyms]
WY-135
WY135,WY 135
2,4-Pyrimidinediamine, 5-chloro-N2-[2-methoxy-4-[4-[(4-methyl-1-piperazinyl)methyl]-1H-1,2,3-triazol-1-yl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]- | [Molecular Formula]
C28H34ClN9O3S | [MDL Number]
MFCD31813638 | [MOL File]
2163060-83-9.mol | [Molecular Weight]
612.15 |
| Hazard Information | Back Directory | [Uses]
WY-135 is an ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor. | [References]
[1] Wang Y, et al. Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R. Eur J Med Chem. 2018 Jan 1;143:123-136. DOI:10.1016/j.ejmech.2017.11.008 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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