| Identification | Back Directory | [Name]
BTC,tetrapotassiumsalt | [CAS]
216453-54-2 | [Synonyms]
BTC (potassium salt)
BTC, tetrapotassium salt *CAS 216453-54-2* | [Molecular Formula]
C33H29K4N3O12S4* | [MOL File]
216453-54-2.mol | [Molecular Weight]
848.054 |
| Hazard Information | Back Directory | [Description]
BTC is a low affinity calcium indicator (Kd = 7-26 μM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements.1 BTC is suitable for detecting elevated calcium levels associated with activation of smooth muscle, neurons, and intracellular calcium stores.1,2
| [Uses]
BTC tetrapotassium is a low affinity calcium indicator (Kd approximately 7-26 μM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg2+, and accuracy of ratiometric measurement[1]. | [storage]
Store at -20°C | [References]
1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications ,(2010).
2. Hyrc, K.L., Bownik, J.M., and Goldberg, M.P. Neuronal free calcium measurement using BTC/AM, a low affinity calcium indicator Cell Calcium 24(3),165-175(1998). |
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