217099-44-0

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217099-44-0 Structure

Identification	Back Directory
[Name] 2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
[CAS] 217099-44-0
[Synonyms] BCX 1470 BCX 1470;BCX-1470;BCX1470 BCX 1470 (Methanesulfonate) 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarbo 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarboxylic acid methanesulfonate 2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1) 2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1) ISO 9001：2015 REACH
[Molecular Formula] C15H14N2O5S3
[MOL File] 217099-44-0.mol
[Molecular Weight] 398.47

Chemical Properties	Back Directory
[storage temp. ] Keep in dark place,Sealed in dry,2-8°C
[solubility ] DMSO: ≥ 33.33 mg/mL (83.64 mM)
[form ] Powder
[color ] White to off-white

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P305+P351+P338

Hazard Information	Back Directory
[Uses] BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
[storage] Store at -20°C
[References] [1] Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement.J Immunol. 2000 Jan 1;164(1):463-8. DOI:10.4049/jimmunol.164.1.463 [2] Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement. J Immunol. 2000 Jan 1;164(1):463-8. DOI:10.4049/jimmunol.164.1.463

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