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2173232-79-4

2173232-79-4 Structure

2173232-79-4 Structure
IdentificationBack Directory
[Name]

LOM612
[CAS]

2173232-79-4
[Synonyms]

LOM612
Naphth[2,3-d]isothiazole-4,9-dione, 3-(dimethylamino)-
[Molecular Formula]

C13H10N2O2S
[MOL File]

2173232-79-4.mol
[Molecular Weight]

258.3
Chemical PropertiesBack Directory
[Boiling point ]

386.2±42.0 °C(Predicted)
[density ]

1.436±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 6 mg/mL (23.23 mM);Water : < 0.1 mg/mL (insoluble)
[form ]

Solid
[pka]

3.04±0.20(Predicted)
[color ]

Pink to red
Hazard InformationBack Directory
[Uses]

LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells[1].
[storage]

Store at -20°C
[References]

[1] Cautain B, et al. Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling. PLoS One. 2016 Dec 9;11(12):e0167491. DOI:10.1371/journal.pone.0167491
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