| Identification | More | [Name]
2-(Trifluoromethyl)benzyl chloride | [CAS]
21742-00-7 | [Synonyms]
2-(TRIFLUOROMETHYL)BENZYL CHLORIDE
ALPHA'-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-XYLENE
TIMTEC-BB SBB006695
1-(chloromethyl)-2-(trifluoromethyl)benzene
o-(Trifluoromethyl)Benzyl Chloride
à'-chloro-à,à,à-trifluoro-o-xylene
α'-chloro-α,α,α-trifluoro-o-xylene
2-(Trifluoromethyl)benzyl chloride 97%
2-(Trifluoromethyl)benzylchloride97%
2-(Trifluoromethyl)benzyl chloride, 98+%
o-Xylene, a'-chloro-a,a,a-trifluoro-
1-(Trifluoromethyl)-2-(chloromethyl)benzene | [EINECS(EC#)]
244-560-6 | [Molecular Formula]
C8H6ClF3 | [MDL Number]
MFCD00009920 | [Molecular Weight]
194.58 | [MOL File]
21742-00-7.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR LIGHT YELLOW LIQUID | [Boiling point ]
67-68°C 12mm | [density ]
1.337 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.469(lit.)
| [Fp ]
158 °F
| [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
clear liquid | [color ]
Colorless to Almost colorless | [Specific Gravity]
1.337 | [Sensitive ]
Lachrymatory | [BRN ]
389380 | [InChI]
1S/C8H6ClF3/c9-5-6-3-1-2-4-7(6)8(10,11)12/h1-4H,5H2 | [InChIKey]
BBXDMCQDLOCXRA-UHFFFAOYSA-N | [SMILES]
FC(F)(F)c1ccccc1CCl | [CAS DataBase Reference]
21742-00-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R36/37:Irritating to eyes and respiratory system . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Corrosive/Lachrymatory | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29039990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
2-(Trifluoromethyl)benzyl chloride is CLEAR LIGHT YELLOW LIQUID
| [Uses]
2-(Trifluoromethyl)benzyl chloride reacts with 2-benzo[b]thienyllithium to yield 6-fluorobenzo[b]naphtho[2,3-d]thiophene. | [Uses]
2-(Trifluoromethyl)benzyl chloride is used in preparation of phenyl-substituted carboxylic acid derivatives as PAI-1 inhibitors.
| [References]
[1] Patent: CN106588673, 2017, A. Location in patent: Paragraph 0049; 0056; 0062
[2] Journal of medicinal chemistry, 1971, vol. 14, # 11, p. 1052 - 1054
[3] Journal of Medicinal Chemistry, 1981, vol. 24, # 4, p. 382 - 389 |
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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http://chemicals.thermofisher.cn |
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Energy Chemical
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www.energy-chemical.com |
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