| Identification | Back Directory | [Name]
BUTEIN | [CAS]
21849-70-7 | [Synonyms]
BUTEIN
C08578
NSC 652892
2',3,4,4'-TETRAHYDROCHALCONE
2',3,4,4'-TETRAHYDROXYCHALCONE
2',4',3,4-TETRAHYDROXYCHALCONE
3,4,2',4'-TETRAHYDROXYCHALCONE
2’,4’-dihydroxy-3-(3,4-dihydroxyphenyl)-acrylophenon
1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-on
1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)- | [Molecular Formula]
C15H12O5 | [MDL Number]
MFCD00017300 | [MOL File]
21849-70-7.mol | [Molecular Weight]
272.25 |
| Chemical Properties | Back Directory | [Melting point ]
250-252℃ | [Boiling point ]
560.9±50.0 °C(Predicted) | [density ]
1.483±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO: >50 mg/mL | [form ]
solid | [pka]
7.34±0.35(Predicted) | [color ]
yellow |
| Hazard Information | Back Directory | [Uses]
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent. | [Definition]
ChEBI: Butein is a chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. It has a role as a tyrosine kinase inhibitor, an antioxidant, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an antineoplastic agent, a geroprotector, a radiosensitizing agent, a hypoglycemic agent and a plant metabolite. It is a member of chalcones and a polyphenol. |
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