| Identification | More | [Name]
Hesperidin methylchalcone | [CAS]
24292-52-2 | [Synonyms]
(E)-3-(3-HYDROXY-4-METHOXY-PHENYL)-1-[2-HYDROXY-6-METHOXY-4-[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-((2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXYMETHYL)-TETRAHYDRO-PYRAN-2-YLOXY]-PHENYL]-PROPENONE
HESPERIDIN METHYL CHALCONE
(e)-osyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)
2’,3,4’-trihydroxy-4,6’-dimethoxy-chalcon4’-(6-o-(6-deoxy-alpha-l-mannopyr
2-propen-1-one,1-[4-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyran
anosyl)-beta-d-glucopyranoside)
Hesperidine Methyl Chalcone
1-[4-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one
HESPERIDIN METHYL CHALCONE*PRACTICAL GRA DE
2-Propen-1-one, 1-4-6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyloxy-2-hydroxy-6-methoxyphenyl-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
(E)-1-(4-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-hydroxy-6-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one
(E)-2',3-Dihydroxy-4,6'-dimethoxy-4'-[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxychalcone | [EINECS(EC#)]
246-128-2 | [Molecular Formula]
C29H36O15 | [MDL Number]
MFCD00010438 | [Molecular Weight]
624.59 | [MOL File]
24292-52-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
120 °C (dec.)(lit.)
| [alpha ]
-71 º (c=1 in ethanol) | [Boiling point ]
583.81°C (rough estimate) | [density ]
1.3090 (rough estimate) | [refractive index ]
1.5940 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.71±0.40(Predicted) | [color ]
Yellow | [Optical Rotation]
[α]20/D 71°, c = 1 in ethanol | [Cosmetics Ingredients Functions]
ANTIOXIDANT | [InChIKey]
FDHNLHLOJLLXDH-JIYHLSBYSA-N | [SMILES]
COc1ccc(\C=C\C(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2OC)cc1O | [LogP]
0.267 (est) | [Uses]
hesperidin methyl chalcone is a citrus bioflavonoid. extracted from the peel of sweet oranges, it has anti-oxidant properties. It is used in eye care preparations for reducing the appearance of dark circles. | [CAS DataBase Reference]
24292-52-2(CAS DataBase Reference) | [EPA Substance Registry System]
24292-52-2(EPA Substance) |
| Hazard Information | Back Directory | [Description]
Hesperidin methylchalcone (HMC) is a flavonoid with potent free radical quenching properties and is a highly complex compound typically found in bright-colored plants and flowers. In skincare, it is primarily used as an antioxidant, with noted effects on circulation for reducing dark circles and melanin synthesis. Hesperidin, in its raw form, has poor absorption. Hence, it is modified into HMC for better stability and skin compatibility. | [benefits]
Hesperidin MethylChalcone (HMC) is a very interesting antioxidant as it is one of the rare Barrier Repair Antioxidants. It is able to increase Filaggrin and B-glucocerebrosidase which are essential for Ceramide production. The other notable use for HMC is its ability to reduce capillary permeability for dark cicles around the eyes.
The benefits of HMC include: Anti-dark Circles, Antioxidant, Barrier Repair, and Anti-aging.
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China Langchem Inc.
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Sigma-Aldrich
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