| Identification | More | [Name]
BUTEIN | [CAS]
487-52-5 | [Synonyms]
1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE
2',3,4,4'-TETRAHYDROCHALCONE
2',3,4,4'-TETRAHYDROXYCHALCONE
2',4',3,4-TETRAHYDROXYCHALCONE
3,4,2',4'-TETRAHYDROXYCHALCONE
BUTEIN
BUTEIN(SH)
BUTEIN WITH HPLC
BUTANOL
1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one
(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one
2',3,4,4'-Tetrahydroxy-trans-chalcone | [EINECS(EC#)]
207-659-5 | [Molecular Formula]
C15H12O5 | [MDL Number]
MFCD00017300 | [Molecular Weight]
272.25 | [MOL File]
487-52-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
216°C | [Boiling point ]
560.9±50.0 °C(Predicted) | [density ]
1.483±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: >50 mg/mL
| [form ]
solid
| [pka]
7.44±0.35(Predicted) | [color ]
yellow
| [InChI]
1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ | [InChIKey]
AYMYWHCQALZEGT-ORCRQEGFSA-N | [LogP]
2.405 (est) | [CAS DataBase Reference]
487-52-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29145090 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent | [Definition]
ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. | [General Description]
Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium). | [Biochem/physiol Actions]
Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
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